Follow up to
This is just a bit more info on using search for targeting guests
A bit about Twitter Search, you can use tweetdeck and tweetlater for this, but this is really fun to poke around in if you have a minute or 3 http://search.twitter.com/ and advanced http://search.twitter.com/advanced
If you want to track “bed and breakfast Maine” you can put this into a group on tweetdeck or “getting married New Hampshire” keep in mind plurals “wedding” and “weddings” will return different things, a search for “wedding NH” turns up the majority of the tweets that appear for this, such as “going to a wedding in NH” or “having a wedding in NH” (also abbreviations, especially states are used a lot, ie the tweet length available) where as “weddings NH” turns up people such as wedding planners or other lodging tweeting about have weddings available in NH. Note the plural it can make a big difference in search.
This is great if you have a few minutes to check some of this out live on twitter search, you would be amazed what people are talking about. You can follow the the people talking about these things, but I would suggest you primarily @theirname and start a conversation with them. If they are using tweetdeck and seismic, it will pop up that someone has corresponded with them.
People do ask questions on twitter of their friends and people they tweet with. “need a suggestion about where to stay in NH” I need a good caterer in NH” “looking for a good bed and breakfast in NH” Play around with keyword combinations and see what you get the most out of.